Home
Back
Cockcroft-Gault Equation for Males:
| From: | To: |
The Cockcroft-Gault equation estimates creatinine clearance (CrCl) from serum creatinine, age, weight, and gender. It is widely used for drug dosing adjustments in patients with renal impairment and for assessing kidney function.
The calculator uses the Cockcroft-Gault equation for males:
Where:
Explanation: The equation estimates the rate at which creatinine is cleared from the blood by the kidneys, providing an approximation of glomerular filtration rate.
Details: Accurate creatinine clearance estimation is crucial for medication dosing adjustments, particularly for drugs that are renally excreted. It helps prevent drug toxicity in patients with impaired kidney function.
Tips: Enter age in years, weight in kilograms, and serum creatinine in mg/dL. All values must be valid (age between 1-120, weight > 0, creatinine > 0).
Q1: What is the difference between CrCl and eGFR?
A: CrCl estimates creatinine clearance specifically, while eGFR estimates glomerular filtration rate. CrCl is often used for drug dosing, while eGFR is used for CKD staging.
Q2: What are normal CrCl values for men?
A: Normal CrCl for adult men is typically 97-137 mL/min, though values decline with age.
Q3: When is this equation not appropriate?
A: Not suitable for patients with unstable creatinine levels, extremes of body composition, amputees, or those with rapidly changing renal function.
Q4: How does weight affect the calculation?
A: The equation uses actual body weight. For obese patients, some clinicians use ideal body weight or adjusted body weight.
Q5: Is this equation validated for all populations?
A: The Cockcroft-Gault equation was developed primarily in hospitalized patients and may overestimate CrCl in elderly and underweight individuals.